Detalhe da pesquisa
1.
An aged immune system drives senescence and ageing of solid organs.
Nature
; 594(7861): 100-105, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33981041
2.
MicroRNA-29a: a novel target for non-operative management of symptomatic lumbar spinal stenosis.
Eur Spine J
; 33(3): 892-899, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-37046075
3.
Protocol for Biospecimen Collection and Analysis Within the BACPAC Research Program.
Pain Med
; 24(Suppl 1): S71-S80, 2023 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36525387
4.
Toward the Identification of Distinct Phenotypes: Research Protocol for the Low Back Pain Biological, Biomechanical, and Behavioral (LB3P) Cohort Study and the BACPAC Mechanistic Research Center at the University of Pittsburgh.
Pain Med
; 24(Suppl 1): S36-S47, 2023 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36715642
5.
The Back Pain Consortium (BACPAC) Research Program Data Harmonization: Rationale for Data Elements and Standards.
Pain Med
; 24(Suppl 1): S95-S104, 2023 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36721327
6.
ISSLS Prize in Bioengineering Science 2022: low rate cyclic loading as a therapeutic strategy for intervertebral disc regeneration.
Eur Spine J
; 31(5): 1088-1098, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35524071
7.
Ionizing Radiation Induces Disc Annulus Fibrosus Senescence and Matrix Catabolism via MMP-Mediated Pathways.
Int J Mol Sci
; 23(7)2022 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35409374
8.
Serum and nutrient deprivation increase autophagic flux in intervertebral disc annulus fibrosus cells: an in vitro experimental study.
Eur Spine J
; 28(5): 993-1004, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30847707
9.
Rapamycin mitigates inflammation-mediated disc matrix homeostatic imbalance by inhibiting mTORC1 and inducing autophagy through Akt activation.
JOR Spine
; 7(1): e1303, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38222800
10.
Immune exposure: how macrophages interact with the nucleus pulposus.
Front Immunol
; 14: 1155746, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37122738
11.
Cellular Senescence in Intervertebral Disc Aging and Degeneration: Molecular Mechanisms and Potential Therapeutic Opportunities.
Biomolecules
; 13(4)2023 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37189433
12.
Percutaneous lumbar annular puncture: A rat model to study intervertebral disc degeneration and pain-related behavior.
JOR Spine
; 5(2): e1202, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35783914
13.
Rabbit Annulus Fibrosus Cells Express Neuropeptide Y, Which Is Influenced by Mechanical and Inflammatory Stress.
Neurospine
; 17(1): 69-76, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-32252156
14.
Oxidative stress-induced senescence markedly increases disc cell bioenergetics.
Mech Ageing Dev
; 180: 97-106, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31002926
15.
Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging.
Redox Biol
; 17: 259-273, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29747066
16.
ADAMTS5 Deficiency Protects Mice From Chronic Tobacco Smoking-induced Intervertebral Disc Degeneration.
Spine (Phila Pa 1976)
; 42(20): 1521-1528, 2017 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28570296
17.
Molecular mechanisms of biological aging in intervertebral discs.
J Orthop Res
; 34(8): 1289-306, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26890203
18.
Catabolic effects of endothelial cell-derived microparticles on disc cells: Implications in intervertebral disc neovascularization and degeneration.
J Orthop Res
; 34(8): 1466-74, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27246627
19.
The effects of glucosamine sulfate on intervertebral disc annulus fibrosus cells in vitro.
Spine J
; 15(6): 1339-46, 2015 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24361347
20.
Investigating the role of DNA damage in tobacco smoking-induced spine degeneration.
Spine J
; 14(3): 416-23, 2014 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24211096